Sorghum bicolor is a species of grass, traditionally cultivated for its nutritious grain. Sorghum is now grown in many tropical and subtropical regions of the world, and is gaining increased popularity as a non-gluten grain. Historical uses of Sorghum include food, hot teas, beers, and traditional medicinal extracts.
Health benefits include
- Multi-facetted anti-inflammatory properties
- Immune activation
- Hematopoietic effect
- Pain reduction
West African Sorghum-based JobelynTM has immue activating properties in laboratory tests
JobelynTM is produced from a unique variety of Sorghum bicolor, recently domesticated from a West African wild variety, representing original genetic makeup and not a result of intense breeding efforts. Jobelyn TM is an extract derived specifically from the intensely colored leaf sheathes. JobelynTM is GRAS-certified by the FDA. JobelynTM has an unusual chemical profile compared to other variants of Sorghum bicolor. It has a very high content of unique antioxidant polyphenols, including unique dimeric 3-deoxyanthocyanidins. Given the traditional use of Sorghum-based products, including teas, in prevention of viral illness, JobelynTM was tested for immune activating properties in laboratory tests.
Our immune system is not limited to a given organ or tissue, but is widespread throughout our body, blood, skin, and mucosal barriers. Immune cells, when activated, communicate in various ways by:
- Expressing receptors on cell surfaces to receive signals.
- Secreting compounds to send signals to other cells.
Jobelyn TM treatment of human immune cells resulted in increased expression of the CD69 activation marker on the cell surface of Natural Killer cells, NKT cells, T lymphocytes, and monocytes. The cytokine profile in these cell cultures showed up-regulation of multiple cytokines, including several chemokines known to be involved in anti-viral immune defenses.